MUSCAT CHEMICAL TAG::
GLYCYL GLYCINE It is used in the synthesis of more complex peptides. Glycylglycine has also been reported to be helpful in solubilizing recombinant proteins in E. coli. Using different concentrations of the glycylglycine improvement in protein solubility after cell lysis has been observed.
The protective action of a series of organic sulfur compounds and amino acids has been investigated by using glycine and glycylglycine as substrates. A linear relationship is shown to exist between the reciprocal of the G-m value for the substrate in the presence of the protecting agent, and the concentration of this protecting agent. The "protecting activity" of the agents, expressed as the ratio of the rate constants for the reaction of radicals with the protecting agent and the substrate, is determined.
Glycylglycine is a dipeptide also used as a buffering agent in enzymatic assays and in medical procedures. Used in ion exchange chromatography. Used as a lysis buffer, running buffer and an enzymatic reaction buffer.