MUSCAT CHEMICAL TAG::
Formamide is a constituent of cryoprotectant vitrification mixtures used for cryopreservation of tissues and organs. Formamide is also used as an RNA stabiliser in gel electrophoresis by deionizing RNA. In capillary electrophoresis, it is used for stabilizing (single) strands of denatured DNA.
Reproductive toxicity in Swiss mice, during chronic exposure to formamide (FORM) or dimethylformamide (DMF), was evaluated.
It is chemical feedstock for the manufacture of sulfa drugs, other pharmaceuticals, herbicides, pesticides and the manufacture of hydrocyanic acid.
The mean fetal body weight per litter was 98, 93, and 85% of the average control weight for the low-, mid-, and high-dose groups.