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RXMARINE CHEMICAL TAG::
2-Methylimidazole is an organic compound that is structurally related to imidazole with the chemical formula CH₃C₃H₂N₂H. It is a white or colorless solid that is highly soluble in polar organic solvents and water. It is a precursor to a range of drugs and is a ligand in coordination chemistry.
Further, it acts as a catalyst for refolding of enhanced colored fluorescent protein. It is also useful as a building block in the synthesis of biologically active compounds. In addition to this, it is used as an active pharmaceutical ingredient intermediate such as metronidazole and dimetridazole.
Physical Properties:
Melting Point | 142-143 °C lit. |
Boiling Point | 267-268 °C lit. |
Density | 1.0500 rough estimate |
Vapour pressure | <1 mm Hg ( 0 °C |
Refractive index | 1.4970 estimate |
Flash Point | 155 °C |
Solublity | 780g/l |
Storage temprature | 2-8°C |
pKa | 14.44±0.10 Predicted |
Form | Crystalline Powder |
Colour | White to light yellow |
PH | 10.5-11.5 |
Solublity | Soluble in water and ethanol |
2-Methylimidazole is used as a raw material for the preparation of nitroimidazole antibiotics, which is useful in combat anaerobic bacterial and parasitic infections. It acts as a ligand in coordination chemistry.
It is also employed as a hardener or accelerator for epoxy resin and auxiliary agent for textile dyes.