Product Application
- 8122620 reads
Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments and suppository base, and tablet and capsule lubricant. ... PEG is also available as a bowel prep for colonoscopy procedures and as a laxative
Polyethylene glycols are non-toxic, odorless, neutral, lubricating, nonvolatile and nonirritating and are used in a variety of pharmaceuticals and in medications as a solvent, dispersing agent, ointment and suppository bases, vehicle, and tablet excipient.
Polyethylene glycols (PEGs) are condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH. They are the most commercially important type of polyether. The low molecular weight compounds up to 700 are colorless, odorless viscous liquids with a freezing point from -10˚C (diethylene gycol), while polymerized compounds with higher molecular weight than 1,000 are wax like solids with melting point up to 67˚C. While PEGs with different molecular weights find use in different applications and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical.
The numbers that are often included in the names of PEGs indicate their average molecular weights, e.g. a PEG with n=9 would have an average molecular weight of approximately 400 and would be labeled PEG 400. Most PEGs include molecules with a distribution of molecular weights, i.e. they are polydisperse.
