Product Application
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Doses up to 25 grams daily for up to 14 days have been safely used. Lower doses up to 4-5 grams taken daily for up to 18 months have also been safely used. Creatine is POSSIBLY SAFE when taken by mouth, long-term. Doses up to 10 grams daily for up to 5 years have been safely used.
Serum creatinine (Scr) is the most commonly used biomarker of kidney function. In the steady-state, serum creatinine can be used to estimate glomerular filtration rate, using the modification of diet in renal disease (MDRD) [1] or chronic kidney disease epidemiology collaboration formulae.
Estimating kidney function is challenging and critically ill patients.
Creatinine is a widely used functional biomarker and has substantial shortcomings.
Use of novel functional biomarkers with creatinine provides additional information.
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
New technologies for direct GFR measurement could overcome creatinine limitations.
New technologies for direct GFR measurement could overcome creatinine limitations.Estimating kidney function is challenging and critically ill patients.
•
Creatinine is a widely used functional biomarker and has substantial shortcomings.
•
Use of novel functional biomarkers with creatinine provides additional information.
•
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
•
New technologies for direct GFR measurement could overcome creatinine limitations.
